Research

My research projects with US, Canadian, Swiss, Dutch and German colleagues are aimed at better understanding the interaction between hormonal changes and mood disorders. Our most recent publications in the journals “Frontiers in Medicine” and “Frontiers in Psychology” provide a good overview of this:

Schweizer-Schubert, S. (2022). Editorial: Endocrinological and Social Moderators of Emotional Well-Being During Perimenstrual, Perinatal and Perimenopausal Transitions: What Women Want for Sexual Health and Smooth Hormonal Changes. Frontiers in Psychology, 12:813291. doi: 10.3389/fpsyg.2021.813291

Schweizer-Schubert, S. et al. (2021). Steroid Hormone Sensitivity in Reproductive Mood Disorders On the Role of the GABA-A Receptor Complex and Stress During Hormonal Transitions. Frontiers in Medicine, 7:479646. doi: 10.3389/fmed.2020.479646

These articles are internationally available from the US National Library of Medicine (as well as other articles, if your want to do a bit of research):
https://pubmed.ncbi.nlm.nih.gov/33585496/

You can download a copy from this website as well:
Download PDF

You can find my other research work on this and other topics at
https://www.researchgate.net/profile/Sophie-Schweizer-Schubert

My current research focus is on the Psychoendocrinology of Female Wellbeing and how to navigate Perimenopausal Women’s Health between Hormonal, Social and Psychological Parameters. In particular those women with a stress reactivity marked by trauma, either to themselves or (epi-)genetically transmitted, and here first and foremost those women choosing motherhood next to a career yet lacking adequate support. We need to create a far better awareness of their vulnerability to long-term stress exposure and resulting hormonal dysbalances that may at first put them in silent discomfort, but gradually build further health risks that may culminate during the menopausal transition when the protective effects of their sex hormones weaken. High cortisol, less progesteron-binding and estrogen dominance may have to be corrected.

Let us revisit female stress, depression and anxiety as identifiers for unmet needs and meet them- in time- by prevention and protection of female health in psychoendocrinological research and practice, not only treatment. And let us be attentive for first signals visible from the outside of the woman’s body: e.g. this may be factors like weight gain, which in turn may fire estrogen dominance and related health risks; visible difficulties to buffer stress in normal daily life etc.